Medical Faculty of Masaryk University, Brno, Czech Republic, invites
excellent scientists to apply for a two-year
POSTDOC POSITION in Cell Biology and Glioblastoma Research
Our laboratory is focused on understanding the biology of glioblastoma
with the ultimate goal of deciphering the molecular mechanisms driving
this aggressive disease and setting up robust systems for drug testing and
development. To achieve these goals, we use a variety of models, including
glioblastoma cell lines, patient-derived samples, and advanced co-culture
systems with human pluripotent stem cell-derived tumoroids.
Our ongoing research includes single-cell sequencing of these co-culture
systems, with future experiments centered around exploring the underlying
molecular pathways and identifying potential treatment strategies. We aim
to establish reproducible 3D systems for drug testing to assess the
efficacy of new therapeutics.
Our lab is an expert environment for studying stem cell biology and
employing stem cell-based models for disease modeling in vitro. We have
well-established methods and protocols for co-culture systems and are
supported by active collaborations with clinicians who provide us with
tumor samples.
Our team currently consists of 10 Postdoctoral Researchers (including 2
bioinformaticians), and 9 undergraduate and graduate students, all
proficient in their respective fields.
The successful candidate should:
Hold a Ph.D. or its equivalent, awarded within the past 7 years, AND
have worked in research in the field of cell biology, cancer biology, or a
closely related area for at least 2 years of work, within the last 3
years , outside the Czech Republic (with a workload equivalent to at
least 0.5 full-time employment)
Alternatively, hold a Ph.D. diploma (or equivalent) from an
international institution awarded within the past 3 years
Demonstrate a strong publication record, with a minimum of three research
outputs in the last three years, at least two of which are in Q1-ranked
journals according to Web of Science
Specific qualifications include:
Have experience in working with glioblastoma models, cancer cell biology,
or stem cell-based disease modeling
Be proficient in advanced cell culture techniques, such as 3D cultures and
co-culture systems
Have prior experience in molecular biology techniques, such as RNA
sequencing, Western blotting, qPCR, immunocytochemistry, or live-cell
imaging
Show an aptitude for designing and executing drug testing protocols,
including the analysis of therapeutic efficacy in 3D systems
Exhibit strong communication and teamwork skills, with a commitment to
collaborative research
Please submit an e-application, including:
A comprehensive CV detailing your publication history
A copy of your diploma
A brief description of your research focus and the specific topic you
intend to investigate
Contact information for two referees
Documentation confirming a minimum of two full years of work outside the
Czech Republic in the last three years or a Ph.D. diploma from a foreign
institution
What we offer:
Access to Core Facilities and state-of-the-art facilities, including
advanced imaging and sequencing technologies
A competitive salary commensurate with the candidate's experience and
expertise
An initial two-year appointment with the possibility of extension
An outstanding research environment with access to state-of-the-art
facilities and equipment
The opportunity to collaborate with a professional team in a stimulating
and supportive work environment
Participation in national and international collaborations, including
opportunities for travel to conferences and short-term research stays
(based on actual project needs)
A tailored welcome service to support the successful candidate and their
family during their transition
Anticipated start date: The position is available from April 2025 or upon
agreement
The submission deadline is 31st January 2025
For more information, please contact Martina Vráblíková by e-mail
[email protected] .
The assessment of applications will begin promptly after the submission
deadline. Shortlisted candidates will be invited for interviews within one
month of the deadline.
