Responsible for the Metabolomics platform

Centro Nacional de Investigaciones Cardiovasculares Carlos III
September 17, 2024
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Offerd Salary:Negotiation
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Working Time:Negotigation
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Status:

Open call

Deadline for submitting applications:

Tuesday, 17 September, 2024

The Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.) CNIC has been conceived to develop research of excellence, competitive and of international relevance in relation to cardiovascular diseases. The CNIC has a research center of 24,000 m2, located in Madrid, with more than 6,000 m2 for laboratories equipped with a state-of-the-art infrastructure and equipment.

CNIC is seeking for a highly motivated and talented candidate with a strong background in metabolomics and lipidomics sciences. A post of "Senior Technician" is advertised. The candidate will direct and coordinate the metabolomics platform within the CNIC Clinical Trial Coordination Unit.

Functions:

  • Lead the daily operation of the metabolomics platform at the CNIC
  • Implement the metabolomics/lipidomics services
  • Implement and yearly update of service fees
  • Conduct and coordinate metabolomics/lipidomics studies inside the CNIC with emphasis on methodologies and expertise related to mass spectrometry
  • Engage with other CNIC research groups to design, plan and execute metabolomics/lipidomics studies
  • Develop and optimize novel methodologies to simultaneously measure large numbers of analytes in biological samples including small molecule biochemicals, metabolites and lipids
  • Setting up in-house untargeted/targeted metabolomics/lipidomics workflows
  • Implement quality assurance and SOPs for metabolomics/lipidomics studies in a production capacity
  • Train and supervise lab technicians' students and other researchers
  • Manage projects efficiently to meet timelines
  • Contribute to writing grant proposal and scientific articles
  • Contribute to strategic scientific and technological development within CNIC objectives
  • Mandatory Requirements:

  • Ph.D. in chemistry or equivalent life science
  • At least 3 years of experience in managing metabolomics/lipidomics core facility or equivalent services' platform or research in these areas.
  • At least one year of postdoctoral experience in a different institution from the PhD
  • Valuable Requirements:

  • C1. Experience in analytical chemistry, particularly in HPLC/UHPLC/GC coupled to mass spectrometry.
  • C2. Experience in shotgun lipidomics.
  • C3. Experience in targeted and untargeted metabolomics and lipidomics, including sample preparation, analysis optimization, method development and data analysis.
  • C4. Experience in carrying out metabolomics/lipidomics experiment with LECO GC-MS and Thermos Orbitrap-MS instruments.
  • C5. Experience in conducting large scale metabolomics study.
  • C6. Underrepresentation of gender by category, in accordance with Action S1 of the 2021-2024 Equality Plan, POSITIVE ACTION IN CALLS FOR POSTS
  • C7. Interview
  • We offer :

  • Opportunity to work in a leading cardiovascular research institution equipped with state-of-the-art resources and technology.
  • Integration in a young translational research team, in a highly competitive environment
  • Start date: Immediate
  • Permanent position (Contrato de duración indefinida), according to “ Tasa de reposición ordinaria autorizada por el Ministerio de Transformación Digital y de la Función Pública para 2024, según resolución de la Dirección General de la Función Pública. N/REF 240206, Resolución del 24 de mayo de 2024 (disposición adicional vigésima segunda de la Ley 31/2022, de 23 de diciembre, de Presupuestos Generales del Estado para el año 2023)”, as long as the selected candidate complies with the legal requirements for the formalization of the contract in accordance with the Spanish labor law.
  • Recruitment Plan:

    The RESOLUTION OF THE SECRETARIAT OF STATE FOR PUBLIC FUNCTION APPROVING THE COMMON ACTION CRITERIA FOR THE RECRUITMENT PROCESSES IN THE STATE PUBLIC SECTOR ENTITIES of April 11, 2022, set forth in point 6.1 that “Unless a specific regulation establishes a merit-based recruitment system (concurso), the competition (concurso-oposición) must be the recruitment system”

    In CNIC, the specific regulations approved by the Foundation's board of trustees establish a merit-based recruitment system (concurso) including a personal interview.

    At least the 3 candidates with the highest score, as long as they reach the minimum of 65 points as a sum of criteria (C1‐C5) will be interviewed. The candidate with the highest score will be hired given the total score (C1-C7) is higher than 80 points.

    Recruitment Commission :

  • Head of Unit
  • Member of Metabolomics Working Group
  • Head of Research Office
  • Manager of the Research Office
  • HR member
  • The CNIC guarantees, within its field of action, the principle of equal access to employment, and may not establish any direct or indirect discrimination, based on grounds of origin, including racial or ethnic origin, sex, age, marital status, religion or beliefs, political opinion, sexual orientation and identity, gender expression, sexual characteristics, trade union membership, social status, language within the State and disability, provided that workers are fit to perform the work or job in question.

    By participating in the selection process, the participant agrees that their data appear in the public resolutions of the selection process. Such resolutions (provisional list of admitted and excluded, definitive list of admitted and excluded and resolution of the process) are published on the CNIC website.

    Scoring Criteria :

  • C1. Experience in analytical chemistry, particularly in HPLC/UHPLC/GC coupled to mass spectrometry (experience will be valued as a whole based on the time/specialty of known techniques). 25%
  • C2. Experience in shotgun lipidomics (experience will be valued as a whole based on the time/specialty of known techniques ). 10%
  • C3. Experience in targeted and untargeted metabolomics and lipidomics, including sample preparation, analysis optimization, method development and data analysis (experience will be valued as a whole based on the time/specialty of known techniques and number of known techniques and strategies). 30%
  • C4. Experience in carrying out metabolomics/lipidomics experiment with LECO GC-MS and Thermos Orbitrap-MS instruments (experience will be valued as a whole based on the time/specialty of known techniques and number of known techniques and strategies). 5%
  • C5. Experience in conducting large scale metabolomics study (experience will be valued as a whole based on the time/specialty of known techniques and number of known techniques and strategies). 5%
  • C6. Underrepresentation of gender by category, in accordance with Action S1 of the 2021-2024 Equality Plan, POSITIVE ACTION IN CALLS FOR POSTS. 5%
  • C7. Interview. 20%
  • Scoring criteria:

    C1 - Experience in analytical chemistry, particularly in HPLC/UHPLC/GC coupled to mass spectrometry - 25%

    C2 - Experience in shotgun lipidomics - 10%

    C3 - Experience in targeted and untargeted metabolomics and lipidomics, including sample preparation, analysis optimization, method development and data analysis - 30%

    C4 - Experience in carrying out metabolomics/lipidomics experiment with LECO GC-MS and Thermos Orbitrap-MS instruments - 5%

    C5 - Experience in conducting large scale metabolomics study - 5%

    C6 - Underrepresentation of gender by category, in accordance with Action S1 of the 2021-2024 Equality Plan, POSITIVE ACTION IN CALLS FOR POSTS - 5%

    C7 - Interview - 20%

    "In the event of absence of any of the evaluators an alternate evaluator of the same area will be appointed"

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