Job Title: Post-Doctoral researcher Department: Department of Surgery
Reporting to: Professor Leonie Young
Location: RCSI, St Stephens Green, Dublin 2
Contract/Duration 2 Years
Remuneration: €43,371
Closing Date: 17.02.2025
About Our Research
RCSI recognises that excellence in research is critical to the quality of its educational activities, its credibility, and, overall, to its mission to enhance human health. RCSI's research strategy aims to build upon its strength in translational biomedical and clinical research to deliver transformational, high impact changes in health care. Targeting both Irish national and EU funding, along with increased collaboration with industry, is a major part of the RCSI research strategy. Forging increased collaboration between RCSI PIs and industry is of critical importance to achieving success in this area. RCSI is also committed to provide its researchers with the supports and developmental opportunities to enable them to continuously grow and support their overall career development.
Summary of Post
Breast cancer brain metastases (BCBM) are a frequent and aggressive form of metastatic spread with limited treatment options. The successful candidate will join Prof Leonie Young and her team to identify the molecular mechanisms controlling the evolution of metastasis in breast cancer and define key regulators of metastatic spread.
The project is funded by an Interreg Atlantic Area award. The objective of this study is to investigate the mechanisms of breast cancer brain metastasis using advanced patient model systems. The research will involve identifying potential drivers and novel therapeutic targets in breast cancer models. The project will generate 3D cell culture systems in conjunction with novel hydrogels from marine organisms. These patient models will be used to perform drug screens and determine therapy response in breast cancer. Techniques employed will include a wide range of molecular biology methods including cell and organoid culture, transcriptomics, protein and sequencing analysis.
The research project will be conducted in a highly collaborative environment. The successful candidate will be expected to design and carry out experimental plans, lead study execution, analyse experimental data, prepare manuscripts and mentor a PhD student. The candidate will also be expected to support other ongoing research projects in the lab.
Specifically, the duties of the post are:
Qualifications – (Essential):
Knowledge & Experience – ( Essential):
We are all too aware that imposter syndrome and the confidence gap can sometimes stop fantastic candidates putting themselves forward, so please do submit an application — we'd love to hear from you.
Application Process
Please apply online through the RCSI careers portal before the closing date with your CV and cover letter.
Informal Enquiries can be directed to [email protected]. Please note we do not accept CVs directly.
Click here to read our Recruitment and Selection Policy for Researcher.
Employee Benefits
RCSI make sure you have the resources you need to thrive by offering a wide range of benefits in areas including time away, finance, community, health, and well-being and insuring your financial future. Below are some additional benefits available to you as an RCSI employee: